Our group develops software and tools in different areas. Below we provide links to different resources. Most of our code is freely accessible and open source. If not specificially stated, we apply a MIT License, i.e. our software is provided as is and without warranties of any kind:
hemoMIPs - targeted sequencing analysis and result reporting pipeline
CADD scripts - scores the deleteriousness of single nucleotide variants and insertion/deletions in the human genome
CADD webserver - data access and download of CADD scores
Saturation Mutagenesis - MPRA visualization of 20 regulatory elements and one ultra conserverd element
ReMM Score - The Regulatory Mendelian Mutation (ReMM) score was created for relevance prediction of non-coding variations (SNVs and small InDels) in the human genome (hg19) in terms of Mendelian diseases.
CADD-SV - CADD-SV is a framework to estimate the impact of Structural Variants in the human genome. We combine various annotations to predict the deleteriousness of human deletions.
Cell-free DNA - analysis of epigenetic signals captured by fragmentation patterns of cell-free DNA.
Cell-free DNA workflows - Workflows for analysing epigenetic signals captured by fragmentation patterns of cell-free DNA.
IBIS - accurate, fast and easy-to-use base caller for the Illumina sequencing system
freeIBIS - accurate, fast and easy-to-use base caller for the Illumina sequencing system
index design - index design and analysis software for highly multiplexed target capture and sequencing.